molecular testing in microbiology
نویسندگان
چکیده
there are significant challenges associated with qualitative and quantitative nucleic acid tests performed in diagnostic laboratories. the development of internationally available certified reference materials which can be traced to reference measurements will contribute to a better understanding of the performance characteristics of nucleic acid tests and enhance reliability and comparability of clinical data. next generation sequencing may have a future role in the identification and resistance detection of clinical pathogens, however, the current complexity of bioinformatics to support this technology makes its routine use in a diagnostic laboratory problematic. however, next generation sequencing is starting to impact epidemiological studies used to investigate the pathways of disease transmission in outbreaks and to determine microbial populations in metagenomics studies.
منابع مشابه
Molecular Testing in Microbiology
There are significant challenges associated with qualitative and quantitative nucleic acid tests performed in diagnostic laboratories. The development of internationally available certified reference materials which can be traced to reference measurements will contribute to a better understanding of the performance characteristics of nucleic acid tests and enhance reliability and comparability ...
متن کاملTowards Multitarget Testing in Molecular Microbiology
Advantages of PCR assays over more conventional culture-based diagnostics include significantly higher sensitivities and shorter turnaround times. They are particularly useful when patient treatment has already been initiated or for specimens that may contain microorganisms that are slow-growing, difficult to culture, or for which culture methods do not exist. However, due to genome variability...
متن کاملMolecular Diagnostics in Clinical Microbiology
In the daily routine of a clinical microbiological laboratory, pathogens can be detected in several ways. Diagnostics of infectious diseases require a strategic approach, since the etiological agent can be of bacterial, viral, fungal or protozoan origin, frequently sharing an identical syndrome. A complicating factor is that the clinical sample, sent to the laboratory, can be severely contamina...
متن کاملMicrobiology and Molecular Genetics
Medical Microbiology & Infectious Diseases: Computerized Teaching Materials and References: Examples of lectures, teaching materials, syllabi, objectives and a disease index can be found at the Kirksville College of Osteopathic Medicine website. Included are Clinical Cases; an Infectious Disease Laboratory Manual; Common Causes of Various Diseases; Notifiable Diseases; Skin Rashes-Diseases; etc...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
research in molecular medicineجلد ۴، شماره ۱، صفحات ۱-۴
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023